1-Genetic and molecular bases of genotype-environment interactions in different organisms, from microorganisms to plants. Proteomic, genomic, transcriptomic analyses. 2-Application of molecular markers to estimate of genetic variability and its bearing with adaptation and fitness 3-Biotechnology for environmental solutions. Phytoremediation, interactions between higher plants and pollutants (both indoor and outdoor), sustainability in agriculture. 4-Traceability of food chains for safety and authenticity: food genomics, proteomics and metabolomics applied to food analysis. 5-Innovative genotoxicological tools, based on chips with cells and biological macromolecules (DNA, proteins). 6-Innovative methodologies to counteract deliberate intrusions into environmental and agri-food resources. 7-Role of miRNA in regulation and response during pathological processes and infection 8-Saccharomyces cerevisiae as a model for human pathologies and ecotoxicological studies