Pompa Andrea Stampa

Cognome e Nome: Pompa Andrea
Qualifica: Professore
Dipartimento: Dipartimento Scienze Biomolecolari
Settore Scientifico Disciplinare: :    BIO 04 ( fisiologia vegetale)
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Cognome e Nome: Ricci Donata
Qualifica:    PA
Dipartimento:  Biomolecular Sciences (DISB)
Ente di appartenenza:  Università di Urbino "Carlo Bo"
Cognome e Nome:  Fraternale Daniele
Qualifica:   Ricercatore confermato
Dipartimento:  Biomolecular Sciences (DISB)
Ente di appartenenza: Università di Urbino "Carlo Bo"
Cognome e Nome:  Giamperi Laura
Qualifica:  Tecnico
Dipartimento: Biomolecular Sciences (DISB)
Ente di appartenenza  Università di Urbino "Carlo Bo"
Cognome e Nome: Bucchini Anahi Ada
Qualifica: Tecnico
Dipartimento:   Biomolecular Sciences (DISB)
Ente di appartenenza   Università di Urbino "Carlo Bo"



- Microsporogenesis and regulatory processes involved in pollen tube emergence and growth. Studies are directed at gaining a better understanding of the basic mechanisms of sexual reproduction in flowering plants, and at evaluating methods for the manipulation of higher plant fertility. In particular, the role of the ubiquitin-dependent proteolytic pathway in the regulation of pollen tube organisation and growth, and the involvement of ubiquitin in the regulation/modulation of the signalling pathway related to this process are investigated. Pollen is a rather unique structure within the plant kingdom; it has certain qualities which make it an ideal model system for basic and applied investigations. It is a natural cellular “vector” and has potential for genetic transformation as it can provide a generally applicable approach to gene transfer in plants. Moreover, pollen grains recall the extraordinary adaptability of microorganisms; haploidy and large population sizes are also peculiar pollen features. Some other characteristics are: ease of storage from harvest until use, simple and quick in vitro culture techniques, fast growth, rapid uptake of externally applied compounds, and no retardation of the drug effect due to diffusion as occurs in a tissue. Most importantly, the high sensitivity of pollen-based assays makes them a suitable and relatively simple, yet reliable, tool to investigate the toxic action of a number of chemicals, both with reference to environmental pollution and acute human toxicity. In this context, we are also using pollen to assess the bioeffects of natural compounds and metabolic inhibitors, and the toxicity of heavy metals and nanoparticles.

- Development of in vitro culture protocols (regeneration and micropropagation) mainly devoted to medicinal plants for secondary metabolite production. Studies on the role played by different endogenous and exogenous factors on in vitro differentiation of plant tissues and organs.

- Extraction of secondary metabolites having antioxidant and antimicrobial activities. Evaluation of antioxidant activity. In vitro and in vivo tests against bacterial and fungal strains.

- Analysis of essential oil composition as a chemotaxonomic marker.


  • Tecniche di colture in vitro
  • Immunoblotting
  • Attività estrattive: clevenger, soxlet, ecc.
  • Tecniche cromatografiche
  • Estrazione e purificazione di proteine
  • Test di tossicità in vivo e in vitro
  • Analisi spettrofotometriche e fluorimetriche


Struttura ove la strumentazione è allocata
Responsabile della strumentazione


Activity of Vitis vinifera Tendrils Extract Against Phytopathogenic Fungi.

Fraternale D, Ricci D, Verardo G, Gorassini A, Stocchia V, Sestili P.

Nat Prod Commun. 2015 Jun;10(6):1037-42.


Essential oil composition and antimicrobial activity of Angelica archangelica L. (Apiaceae) roots.

Fraternale D, Flamini G, Ricci D.

J Med Food. 2014 Sep;17(9):1043-7. doi: 10.1089/jmf.2013.0012.


Proteomic analysis of MG132-treated germinating pollen reveals expression signatures associated with proteasome inhibition.

Vannini C, Bracale M, Crinelli R, Marconi V, Campomenosi P, Marsoni M, Scoccianti V.

PLoS One. 2014 Sep 29;9(9):e108811. doi: 10.1371/journal.pone.0108811.


Role of the ubiquitin-proteasome pathway and some peptidases during seed germination and copper stress in bean cotyledons.

Karmous I, Chaoui A, Jaouani K, Sheehan D, El Ferjani E, Scoccianti V, Crinelli R.

Plant Physiol Biochem. 2014 Mar;76:77-85. doi: 10.1016/j.plaphy.2013.12.025.


Salvia x jamensis J. Compton: Trichomes, essential oil constituents and cytotoxic-apoptotic activity.

Fraternale D, Albertini MC, Rudov A, Flamini G, Ricci D, Bisio A, Battistelli M, Accorsi A.

Nat Prod Res. 2013;27(17):1583-8. doi: 10.1080/14786419.2012.730044.


Over-accumulation of putrescine induced by cyclohexylamine interferes with chromium accumulation and partially restores pollen tube growth in Actinidia deliciosa.

Scoccianti V, Iacobucci M, Speranza A, Antognoni F.

Plant Physiol Biochem. 2013 Sep;70:424-32. doi: 10.1016/j.plaphy.2013.06.004.


In vitro toxicity of silver nanoparticles to kiwifruit pollen exhibits peculiar traits beyond the cause of silver ion release.

Speranza A, Crinelli R, Scoccianti V, Taddei AR, Iacobucci M, Bhattacharya P, Ke PC.

Environ Pollut. 2013 Aug;179:258-67. doi: 10.1016/j.envpol.2013.04.021.

Anti-inflammatory, antioxidant and antifungal furanosesquiterpenoids isolated from Commiphora erythraea (Ehrenb.) Engl. resin.

Fraternale D, Sosa S, Ricci D, Genovese S, Messina F, Tomasini S, Montanari F, Marcotullio MC.

Fitoterapia. 2011 Jun;82(4):654-61. doi: 10.1016/j.fitote.2011.02.002.


Phytotoxic clerodane diterpenes from Salvia miniata Fernald (Lamiaceae).

Bisio A, Damonte G, Fraternale D, Giacomelli E, Salis A, Romussi G, Cafaggi S, Ricci D, De Tommasi N.

Phytochemistry. 2011 Feb;72(2-3):265-75. doi: 10.1016/j.phytochem.2010.11.011.


Pd-nanoparticles cause increased toxicity to kiwifruit pollen compared to soluble Pd(II).

Speranza A, Leopold K, Maier M, Taddei AR, Scoccianti V.

Environ Pollut. 2010 Mar;158(3):873-82. doi: 10.1016/j.envpol.2009.09.022.



Componente U.O. Dottorato di Ricerca Coordinatore Sede
Valeria Scoccianti Scienze della Vita, Salute e Biotecnologie. Prof. Elisabetta Falcieri Urbino


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