Direzione e uffici C.I.B.

Direzione CIB:
Prof. Claudio Schneider
Email: claudio.schneider@Lncib.it

Segreteria CIB:
Prof. Roberto Gambari
Email: roberto.gambari@unife.it

SEGRETERIA ORGANIZZATIVA:
Elisabetta Lambertini
Tel: 0532/974451
Fax: 0532/974484
E-mail: lmblbt@unife.it

AMMINISTRAZIONE:
Vanessa Florit
Area di Ricerca
Padriciano, 99 - 34012 Trieste
Tel: 040/398979
Fax: 040/398990
E-mail: cib@lncib.it

Posta certificata C.I.B.:
cib@poste-certificate.it

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Capella Carlo Renato Stampa
RESPONSABILE DELLA U. O.

Cognome e Nome Capella Carlo Renato
Qualifica Full Professor of Pathology
Facoltà Medicine and Surgery
Dipartimento Human Morphology
Settore Scientifico Disciplinare MED/08
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PERSONALE STRUTTURATO

Cognome e Nome
Bernasconi Barbara
Qualifica Technician
Dipartimento Human Morphology
Ente di appartenenza University of Insubria Varese
Cognome e Nome Cerutti Roberta
Qualifica Technician
Dipartimento Human Morphology
Ente di appartenenza University of Insubria Varese
Cognome e Nome
Furlan Daniela
Qualifica RU
Dipartimento Human Morphology
Ente di appartenenza University of Insubria Varese
Cognome e Nome
Riva Cristina
Qualifica
PA
Dipartimento Human Morphology
Ente di appartenenza University of Insubria Varese
Cognome e Nome
Uccella Silvia
Qualifica RU
Dipartimento Human Morphology
Ente di appartenenza University of Insubria Varese
Cognome e Nome
Qualifica
Dipartimento
Ente di appartenenza

PERSONALE NON STRUTTURATO

Cognome e Nome Carnevali Ileana Wanda
Qualifica PhD student, Experimental Medicine and Oncology
Dipartimento
Human Morphology
Ente di appartenenza
University of Insubria Varese
Cognome e Nome
Marchet Silvia
Qualifica
Research Fellow
Dipartimento
Human Morphology
Ente di appartenenza
University of Insubria Varese
Cognome e Nome
Placidi Claudia
Qualifica
Research Fellow
Dipartimento
Human Morphology
Ente di appartenenza
University of Insubria Varese
Cognome e Nome
Sahnane Nora
Qualifica
Research Fellow
Dipartimento
Human Morphology
Ente di appartenenza
University of Insubria Varese
Cognome e Nome
Qualifica
Dipartimento
Ente di appartenenza
Cognome e Nome
Qualifica
Dipartimento
Ente di appartenenza

LINEE DI RICERCA

• Neuroendocrine pathology Morphological and molecular characterization of neuroendocrine tumors Immunohistochemical expression of growth factors and their receptor in neuroendocrine tumors Amine biosynthesis and storage in neuroendocrine tumors
• Hemo-lymphopathology Classification criteria, molecular profile and prognostic markers of MALT lymphomas of the stomach Morphological and molecular characterization of diffuse large B-cell lymphoma: identification of the cell of origin; relation of gene rearrangements with the biomorphologic profile.
• Gastroenteropancreatic pathology Morphological and molecular characterization of gastric, colorectal and pancreatic carcinomas The hypoxic response in colorectal carcinomas and correlations with invasive growth and metastasis
• Clinicopathological and phenotypic profile of ovarian and endometrial tumors
• Morphological and molecular aspects of diabetic microangiopathy; morphological and molecular features of transplanted islets
• Morphology, immunoprofile and molecular aspects of breast carcinoma
• Role of de novo methylation of gene promoters in the pathogenesis of gliomas, diffuse large B-cell lymphomas and epithelial cancers of various sites
• Molecular basis of hereditary breast-ovarian carcinomas and of hereditary non polyposis colorectal carcinoma

TECNOLOGIE IN POSSESSO DELL'U. O.

  • Immunohistochemistry
  • Electron Microscopy
  • Classical and molecular cytogenetics
  • DNA Sequencing
  • DNA fragment analysis
  • Gene expression analysis by quantitative Real time PCR
  • Gene mutation detection

STRUMENTAZIONE

Denominazione
Struttura ove la strumentazione è allocata
Responsabile della strumentazione
Tesi Imaging Cromowin System
Anatomic Pathology Laboratory, Dpt of Human Morphology
Dott.ssa Tibiletti
Electron Microscope
Anatomic Pathology Laboratory, Dpt of Human Morphology
Dott.ssa Usellini
Denaturing High Performance Liquid Chromatography
Anatomic Pathology Laboratory, Dpt of Human Morphology
Dott.ssa Furlan
ABI 310 DNA Automated Sequencer
Anatomic Pathology Laboratory, Dpt of Human Morphology
Dott.ssa Cerutti
7000 Sequence Detection System for Real time PCR
Anatomic Pathology Laboratory, Dpt of Human Morphology
Dott.ssa Cerutti

PUBBLICAZIONI

Furlan D, Casati B, Cerutti R, Facco C, Terracciano L, Capella C, Chiaravalli AM. Genetic progression in sporadic endometrial and gastrointestinal cancers with high microsatellite instability. J Pathol. 2002 Aug;197(5):603-9.

La Rosa S, Uccella S, Marchet S, Capella C, Lloyd RV. Localization of inhibins and activins in normal endocrine cells and endocrine tumors of the gut and pancreas: an immunohistochemical and in situ hybridization study. J Histochem Cytochem. 2004 Feb;52(2):217-25.

Furlan D, Cerutti R, Uccella S, La Rosa S, Rigoli E, Genasetti A, Capella C. Different molecular profiles characterize well-differentiated endocrine tumors and poorly differentiated endocrine carcinomas of the gastroenteropancreatic tract. Clin Cancer Res. 2004 Feb 1;10(3):947-57.

Riva C, Dainese E, Caprara G, Rocca PC, Massarelli G, Tot T, Capella C, Eusebi V. Immunohistochemical study of androgen receptors in breast carcinoma. Evidence of their frequent expression in lobular carcinoma. Virchows Arch. 2005 Oct;447(4):695-700.

Furlan D, Bernasconi B, Uccella S, Cerutti R, Carnevali I, Capella C. Allelotypes and fluorescence in situ hybridization profiles of poorly differentiated endocrine carcinomas of different sites. Clin Cancer Res. 2005 Mar 1;11(5):1765-75.

Furlan D, Carnevali I, Marcomini B, Cerutti R, Dainese E, Capella C, Riva C. The high frequency of de novo promoter methylation in synchronous primary endometrial and ovarian carcinomas. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3329-36.

Tibiletti MG, Milani K, Martin V, Zucca E, Motta T, Cortelazzo S, Pinotti G, Mazzucchelli L, Pruneri G, Martinelli G., Barbazza R, Capella C, Bertoni F; International Extranodal Lymphoma Study Group (IELSG). Chromosome instability and translocation t(11;18) in primary gastric marginal zone B-cell lymphoma of MALT-type. Hematol Oncol. 2007 Dec;25(4):184-8.

Bernasconi B, Karamitopolou-Diamantiis E, Tornillo L, Lugli A, Di Vizio D, Dirnhofer S, Wengmann S, Glatz-Krieger K, Fend F, Capella C, Insabato L, Terracciano LM. Chromosomal instability in gastric mucosa-associated lymphoid tissue lymphomas: a fluorescent in situ hybridization study using a tissue microarray approach. Hum Pathol. 2008 Apr;39(4):536-42.

Bertolini V, Chiaravalli AM, Klersy C, Placidi C, Marchet S, Boni L, Capella C. Gastrointestinal stromal tumors-frequency, malignancy, and new prognostic factors: The experience of a single institution. Pathol Res Pract. 2008;204(4):219-33.

Furlan D, Sahnane N, Carnevali I, Cerutti R, Uccella S, Bertolini V, Chiaravalli AM, Capella C. Up-regulation of Hypoxia-Inducible Factor-1 (HIF-1) transcriptional pathway in colorectal carcinomas. Human Pathology 2008, in press.

DOTTORATI DI RICERCA

Componente U.O. Dottorato di Ricerca Coordinatore Sede
Prof. Capella Carlo Renato
Experimental Medicine and Oncology
Prof. Accolla Roberto
Department of Clinical and Biological Sciences
Prof. Riva Cristina
Experimental Medicine and Oncology
Prof. Accolla Roberto
Department of Clinical and Biological Sciences
Dott.ssa Uccella Silvia
Experimental Medicine and Oncology
Prof. Accolla Roberto
Department of Clinical and Biological Sciences

CONGRESSI C.I.B.

Congressi Partecipazione
CNB4

CNB5

CNB6

CNB7

CNB8

CNB9
CNB10